Article
The value of structural variants to conservation genomics in the pangenome era.
The Journal of heredity - 3 Sept 2026
Pegan Teresa M, Sivakumar Ashwin H, Burns Christian A, Lopez Kelsie A, Fang Bohao, Melendez Nicole M, Bartel Lauren, Edwards Scott V
Abstract excerpt
Structural variants (SVs) comprise an axis of genetic diversity with strong consequences for phenotype and fitness, making them a potentially important target for conservation genomics. Here, we review how and why SVs can play a role in conservation genomics; the different types of SVs and how they can affect phenotype; and how pangenomes and long-read sequencing are illuminating their evolution in populations,...
Read the complete abstract on PubMedTopics
- Genomic Structural Variation
- Genomics
- Genetic Variation
- Animals
- Genetics, Population
- Evolution, Molecular
