Article
The Impact of Patterns in Linkage Disequilibrium and Sequencing Quality on the Imprint of Balancing Selection.
Genome biology and evolution - 1 Feb 2024
Hayeck Tristan J, Li Yang, Mosbruger Timothy L, Bradfield Jonathan P, Gleason Adam G, Damianos George, Shaw Grace Tzun-Wen, Duke Jamie L, Conlin Laura K, Turner Tychele N, Fernández-Viña Marcelo A, Sarmady Mahdi, Monos Dimitri S
Abstract excerpt
Regions under balancing selection are characterized by dense polymorphisms and multiple persistent haplotypes, along with other sequence complexities. Successful identification of these patterns depends on both the statistical approach and the quality of sequencing. To address this challenge, at first, a new statistical method called LD-ABF was developed, employing efficient Bayesian techniques to effectively...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.