Article
Women's reproductive risk and genetic predisposition in type 2 diabetes: A prospective cohort study.
Diabetes research and clinical practice - 1 Feb 2024
Liu Xiaojing, Liu Xiaowen, Huang Ninghao, Yang Zeping, Zhang Ziyi, Zhuang Zhenhuang, Jin Ming, Li Nan, Huang Tao
Abstract excerpt
OBJECTIVE: To assess synergistic effects of reproductive factors and gene-reproductive interaction on type 2 diabetes (T2D) risk, also the extent to which the genetic risk of T2D can be affected by reproductive risk. METHODS: 84,254 women with genetic data and reproductive factors were enrolled between 2006 and 2010 in the UK Biobank. The reproductive risk score (RRS) was conducted based on 17 reproductive items,...
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