Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Role of Increased Expression of Sirtuin 6 in the Prevention of Premature Aging Pathomechanisms

2 Jun 2023

Abstract excerpt

Sirtuins, in mammals, are a group of seven enzymes (SIRT1–SIRT7) involved in the post-translational modification of proteins—they are considered longevity proteins. SIRT6, classified as class IV, is located on the cell nucleus; however, its action is also connected with other regions, e.g., mitochondria and cytoplasm. It affects many molecular pathways involved in aging: telomere maintenance, DNA repair,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue and Metabolism
Share to Autophagy in Disease and Therapy
Share to Sirtuins and Resveratrol in Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37298604
DOI: 10.3390/ijms24119655

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Role of Increased Expression of Sirtuin 6 in the Prevention of Premature Aging PathomechanismsPMID 37298604Read ↗

SIRT1 and SIRT6: The role in aging-related diseasesSemantic proximity Read ↗

A Review of the Recent Advances Made with SIRT6 and its Implications on Aging Related Processes, Major Human Diseases, and Possible Therapeutic TargetsSemantic proximity Read ↗

Sirt6 Deacetylase: A Potential Key Regulator in the Prevention of Obesity, Diabetes and Neurodegenerative DiseaseSemantic proximity Read ↗

SIRT2 as a Therapeutic Target for Age-Related DisordersSemantic proximity Read ↗

The influential responsibility of sirtuins in senescence and associated diseases: A reviewSemantic proximity Read ↗

Role of sirtuins in epigenetic regulation and aging controlSemantic proximity Read ↗

Sirtuins, a promising target in slowing down the ageing processSemantic proximity Read ↗

High Levels of SIRT1 Expression as a Protective Mechanism Against Disease-Related ConditionsSemantic proximity Read ↗

SIRT1: new avenues of discovery for disorders of oxidative stressSemantic proximity Read ↗

SIRT6: Novel Mechanisms and Links to Aging and DiseaseSemantic proximity Read ↗

The role of sirtuins in aging and age-related diseasesSemantic proximity Read ↗

SIRT7: the seventh key to unlocking the mystery of agingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.