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Article

Effects of G and SH Truncation on the Replication, Virulence, and Immunogenicity of Avian Metapneumovirus

21 Jan 2024

Abstract excerpt

Four mutants varying the length of the G and SH genes, including a G-truncated mutant (ΔG) and three G/SH-truncated mutants (ΔSH/G-1, ΔSH/G-2, and ΔSH/G-3), were generated via serially passaging the avian metapneumovirus strain SNU21004 into the cell lines Vero E6 and DF-1 and into embryonated chicken eggs. The mutant ΔG particles resembled parental virus particles except for the variance in the density of their...

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PMID: 38276678
DOI: 10.3390/vaccines12010106

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