Article
Establishment of reverse genetics for genotype VII Newcastle disease virus and altering the cell tropism by inserting TMPRSS2 into the viral genome.
Virus genes - 1 Aug 2023
Wu Jing, Lu Rongguang, Wang Jigui, Su Jun, Gu Chenchen, Xie Qianqian, Zhu Hui, Xiao Jun, Liu Weiquan
Abstract excerpt
Newcastle disease (ND) is the most important infectious disease in poultry, which is caused by avian orthoavulavirus type 1 (AOAV-1), previously known as Newcastle disease virus (NDV). In this study, an NDV strain SD19 (GenBank accession number OP797800) was isolated, and phylogenetic analysis suggested the virus belongs to the class II genotype VII. After generating wild-type rescued SD19 (rSD19), the...
Topics
Join the communities discussing this publication.