Article
An epigenetic perspective on tumorigenesis: Loss of cell identity, enhancer switching, and NamiRNA network.
Seminars in cancer biology - 1 Aug 2019
Liang Ying, Xu Peng, Zou Qingping, Luo Huaibing, Yu Wenqiang
Abstract excerpt
Various tumorigenic theories have been proposed in the past century, which contribute to the prevention and treatment of cancer clinically. However, the underlying mechanisms of the initiation of cancer, drug resistance, neoplasm relapse, and metastasis are still challenging to be panoramically addressed. Based on the abundant evidence provided by others and us, we postulate that Tumor Initiated by Loss of Cell...
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