Article
Predictors of Clonality and Underlying Mastocytosis in Mast Cell Activation Syndromes.
Current allergy and asthma reports - 1 Feb 2024
Gonzalez-de-Olano David, Álvarez-Twose Iván
Abstract excerpt
PURPOSE OF REVIEW: Mast cell (MC) activation can present with a wide range of symptoms. The mechanisms that cause such activation are varied. One of them is the presence of clonal MCs which is defined, within other possible changes, by the presence of a somatic, activating mutation in the KIT gene. The clinical course and prognosis of patients with this underlying disease may be different from other causes of MC...
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