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Mastocytosis and Mast Cell Activation Disorders: Clearing the Air

19 Oct 2021

Abstract excerpt

Mast cells are derived from hematopoietic stem cell precursors and are essential to the genesis and manifestations of the allergic response. Activation of these cells by allergens leads to degranulation and elaboration of inflammatory mediators, responsible for regulating the acute dramatic inflammatory response seen. Mast cells have also been incriminated in such diverse disorders as malignancy, arthritis,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34681933
DOI: 10.3390/ijms222011270

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