Article
Mastocytosis demystified.
Hematology. American Society of Hematology. Education Program - 8 Dec 2023
Veitch Scott, Radia Deepti H
Abstract excerpt
Mastocytosis is a rare, clinically heterogenous clonal hematological neoplasm. Over 95% of patients harbor the driver KIT D816V mutation resulting in mast cell (MC) accumulation and proliferation in various organs, leading to variable symptom manifestations that result from MC mediator release in patients with systemic mastocytosis (SM) and end-organ damage in those with advanced SM. The accurate diagnostic and...
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