Article
Clonality and molecular pathogenesis of mastocytosis.
Acta haematologica - 1 Jan 2005
Akin Cem
Abstract excerpt
Mast cell is a hematopoietic lineage dependent on Kit signaling for growth, differentiation, and survival. Mast cells are found in excessive numbers in tissues in a heterogeneous group of disorders collectively known as mastocytosis. Last decade has witnessed important advancements in our understanding of the molecular pathology of mastocytosis. First, systemic mastocytosis has been found to be associated with...
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