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Article

Motion of VAPB molecules reveals ER-mitochondria contact site subdomains.

Nature - 1 Feb 2024

Obara Christopher J, Nixon-Abell Jonathon, Moore Andrew S, Riccio Federica, Hoffman David P, Shtengel Gleb, Xu C Shan, Schaefer Kathy, Pasolli H Amalia, Masson Jean-Baptiste, Hess Harald F, Calderon Christopher P, Blackstone Craig, Lippincott-Schwartz Jennifer

Abstract excerpt

To coordinate cellular physiology, eukaryotic cells rely on the rapid exchange of molecules at specialized organelle-organelle contact sites1,2. Endoplasmic reticulum-mitochondrial contact sites (ERMCSs) are particularly vital communication hubs, playing key roles in the exchange of signalling molecules, lipids and metabolites3,4. ERMCSs are maintained by interactions between complementary tethering molecules on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38267577
DOI: 10.1038/s41586-023-06956-y
PMCID: PMC10830423

Genes

VAPB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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