Article

SPtsAnalysis: a high-throughput super-resolution single particle trajectory analysis to reconstruct organelle dynamics and membrane re-organization

2021-09-19

Abstract excerpt

Super-resolution imaging can generate thousands of single-particle trajectories. These data can potentially reconstruct subcellular organization and dynamics, as well as measure disease-linked changes. However, computational methods that can derive quantitative information from such massive datasets are currently lacking. Here we present data analysis and algorithms that are broadly applicable to reveal local bind...

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Literature Corpus work: fbd5090d-6cc9-5d78-8484-c8c74b08ab93
DOI: 10.1101/2021.09.18.460892

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