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Article

CETP gene polymorphisms and haplotypes are explanatory variables for HDL cholesterol level in sickle cell disease.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Jan 2024

Cruz N R C, Valente T N S, Ferreira F O, Macedo L R, Belisário A R, Silva C M da, Oliveira N S, Gomides A F F, Velloso-Rodrigues C

Abstract excerpt

Variations in lipid profile have been observed in sickle cell disease (SCD) and understanding their relationship with disease severity is crucial. This study aimed to investigate the association of polymorphisms of the CETP gene and laboratory markers of disease severity with lipid profile in a pediatric population with SCD. Biochemical and anthropometric analyses and CETP and alpha-thalassemia genotyping were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38265339
DOI: 10.1590/1414-431X2023e12879
PMCID: PMC10802225

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