Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Unveiling the Potential of Nelumbo nucifera-Derived Liensinine to Target The Myostatin Protein and to Counteract Muscle Atrophy

23 Jan 2024

Abstract excerpt

Muscle atrophy refers to a decline in muscle mass and function, which has become a global concern due to the aging population. Various clinical trials have investigated the inhibitors of myostatin (MSTN). They have shown promising improvements in muscle function and quality of life. However, there are no drugs specifically targeting MSTN that have been approved for clinical use. In this study, we virtually...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Treatment and Pharmacology
Share to Muscle Physiology and Disorders
Share to Sirtuins and Resveratrol in Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38258624
DOI: 10.1021/acs.jafc.3c09002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Unveiling the Potential of Nelumbo nucifera-Derived Liensinine to Target The Myostatin Protein and to Counteract Muscle AtrophyPMID 38258624Read ↗

Morroniside ameliorates inflammatory skeletal muscle atrophy via inhibiting canonical and non-canonical NF-κB and regulating protein synthesis/degradationSemantic proximity Read ↗

IMB0901 inhibits muscle atrophy induced by cancer cachexia through MSTN signaling pathwaySemantic proximity Read ↗

Muscular Dystrophies and Therapeutic Potential of Medicinal PlantsSemantic proximity Read ↗

Principles of the activin receptor signaling pathway and its inhibitionSemantic proximity Read ↗

Systems-based Discovery of Tomatidine as a Natural Small Molecule Inhibitor of Skeletal Muscle AtrophySemantic proximity Read ↗

INVITED REVIEW: Inhibitors of myostatin as methods of enhancing muscle growth and development.Semantic proximity Read ↗

Therapeutic applications and challenges in myostatin inhibition for enhanced skeletal muscle mass and functionsSemantic proximity Read ↗

Potent and durable gene modulation in heart and muscle with chemically defined siRNAsSemantic proximity Read ↗

[Myostatin blockade therapy for muscular atrophy].Semantic proximity Read ↗

Loganin possesses neuroprotective properties, restores SMN protein and activates protein synthesis positive regulator Akt/mTOR in experimental models of spinal muscular atrophy.Semantic proximity Read ↗

Myostatin Inhibitors: Panacea or Predicament for Musculoskeletal Disorders?Semantic proximity Read ↗

A muscle growth-promoting treatment based on the attenuation of activin/myostatin signalling results in long-term testicular abnormalities.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.