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Article

Principles of the activin receptor signaling pathway and its inhibition

21 Apr 2021

Abstract excerpt

This review captures the anabolic and stimulatory effects observed with inhibition of the transforming growth factor β superfamily in muscle, blood, and bone. New medicinal substances that rectify activin, myostatin, and growth differentiation factor 11 signaling give hope to the many whose lives are affected by deterioration of these tissues. The review first covers the origin, structure, and common pathway of...

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PMID: 33933900
DOI: 10.1016/j.cytogfr.2021.04.001

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