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Article

Caveolin-3 and Caveolin-1 Interaction Decreases Channel Dysfunction Due to Caveolin-3 Mutations.

International journal of molecular sciences - 12 Jan 2024

Benzoni Patrizia, Gazzerro Elisabetta, Fiorillo Chiara, Baratto Serena, Bartolucci Chiara, Severi Stefano, Milanesi Raffaella, Lippi Melania, Langione Marianna, Murano Carmen, Meoni Clarissa, Popolizio Vera, Cospito Alessandro, Baruscotti Mirko, Bucchi Annalisa, Barbuti Andrea

Abstract excerpt

Caveolae constitute membrane microdomains where receptors and ion channels functionally interact. Caveolin-3 (cav-3) is the key structural component of muscular caveolae. Mutations in CAV3 lead to caveolinopathies, which result in both muscular dystrophies and cardiac diseases. In cardiomyocytes, cav-1 participates with cav-3 to form caveolae; skeletal myotubes and adult skeletal fibers do not express cav-1. In...

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Identifiers

PMID: 38256054
DOI: 10.3390/ijms25020980
PMCID: PMC10816214

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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