Causal association between colorectal cancer and Alzheimer’s disease: a bidirectional two-sample mendelian randomization study

Abstract excerpt

Background: Colorectal cancer and Alzheimer’s disease are both common life-threatening diseases in the elderly population. Some studies suggest a possible inverse relationship between colorectal cancer and Alzheimer’s disease, but real-world research is subject to many biases. We hope to clarify the causal relationship between the two through a bidirectional two-sample Mendelian randomization study. Methods: In...

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