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Article

New mutation within a common haplotype is associated with calf muscle weakness in Holsteins.

Journal of dairy science - 1 Jun 2024

Al-Khudhair A, VanRaden P M, Null D J, Neupane M, McClure M C, Dechow C D

Abstract excerpt

A recessive haplotype resulting in elevated calf mortality but with apparent incomplete penetrance was previously linked to the end of chromosome 16 (78.7-80.7 Mbp). Genotype analysis of 5.6 million Holsteins indicated that the haplotype was common and traced back to 1952, with a key ancestor born in 1984 (HOUSA1964484, Southwind) identified from chip genotypes as homozygous for the suspect haplotype. Sequence...

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Source

Identifiers

PMID: 38246543
DOI: 10.3168/jds.2023-24121

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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