Article
A clinical case of CACNA1S-related muscle weakness in a Holstein calf with congenital astasia diagnosed by a genotyping test of stored blood.
The Journal of veterinary medical science - 1 Jan 2025
Inokuma Hisashi, Maezawa Masaki, Miyazaki Yoshiyuki, Ogino Atsushi, Watanabe Ken-Ichi, Kobayashi Yoshiyasu
Abstract excerpt
A homozygous calf with CACNA1S-related muscle weakness, a new autosomal recessive congenital disorder in Holstein cattle, was identified by genotyping 195 stored blood samples from Holstein calves aged less than 12 months. The patient was an 8-day-old male calf with congenital astasia which presented to a university hospital in 2019. The patient was unable to maintain an upright position with assistance to stand....
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