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Article

RT-PCR genotyping assays to identify SARS-CoV-2 variants in England in 2021: a design and retrospective evaluation study.

The Lancet. Microbe - 1 Feb 2024

Bray Neil, Sopwith Will, Edmunds Matt, Vansteenhouse Harper, Feenstra Jelena D M, Jacobs Peter, Rajput Kamal, O'Connell Anne Marie, Smith Melanie L, Blomquist Paula, Hatziioanou Diane, Elson Richard, Vivancos Roberto, Gallagher Eileen, Wigglesworth Mark J, Dominiczak Anna, Hopkins Susan, Lake Iain R

Abstract excerpt

BACKGROUND: Whole-genome sequencing (WGS) is the gold standard diagnostic tool to identify and genetically characterise emerging pathogen mutations (variants), but cost, capacity, and timeliness limit its use when large populations need rapidly assessing. We assessed the potential of genotyping assays to provide accurate and timely variant information at scale by retrospectively examining surveillance for...

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PMID: 38244555
DOI: 10.1016/S2666-5247(23)00320-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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