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A Prospective Diagnostic Study to Measure the Accuracy of Detection of SARS-CoV-2 Variants Of Concern (VOC) Utilising a Novel RT-PCR GENotyping Algorithm in an <i>in silico</i> Evaluation (VOC-GENIE)

2021-05-08

Abstract excerpt

Background: SARS-CoV-2 variants of concern (VOCs) have been associated with higher rate of transmission, and evasion of immunisation and antibody therapeutics. Variant sequencing is widely utilized in the UK. However, only 0.5% (~650k) of the 133 million cumulative positive cases worldwide were sequenced (in GISAID) on 08 April 2021 with 97% from Europe and North America and only ~0.25% (~320k) were variant sequen...

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Literature Corpus work: aab4ba99-206d-517b-aae9-f51fc2825faf
DOI: 10.2139/ssrn.3835132

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