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Article

Multiplex SARS-CoV-2 Genotyping Reverse Transcriptase PCR for Population-Level Variant Screening and Epidemiologic Surveillance.

Journal of clinical microbiology - 19 Jul 2021

Wang Hannah, Miller Jacob A, Verghese Michelle, Sibai Mamdouh, Solis Daniel, Mfuh Kenji O, Jiang Becky, Iwai Naomi, Mar Marilyn, Huang ChunHong, Yamamoto Fumiko, Sahoo Malaya K, Zehnder James, Pinsky Benjamin A

Abstract excerpt

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with concerning phenotypic mutations is of public health interest. Genomic surveillance is an important tool for a pandemic response, but many laboratories do not have the resources to support population-level sequencing. We hypothesized that a nucleic acid amplification test (NAAT) to genotype mutations in the viral spike...

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Identifiers

PMID: 34037430
DOI: 10.1128/JCM.00859-21
PMCID: PMC8373211

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