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Efficient SARS-CoV-2 Surveillance during the Pandemic-Endemic Transition Using PCR-Based Genotyping Assays.

Microbiology spectrum - 15 Jun 2023

Koets Lianne, van Leeuwen Karin, Derlagen Maaike, van Wijk Jalenka, Keijzer Nadia, Feenstra Jelena D M, Gandhi Manoj, Sorel Oceane, van de Laar Thijs J W, Koppelman Marco H G M

Abstract excerpt

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants of concern (VOC) pose an increased risk to public health due to higher transmissibility and/or immune escape. In this study, we assessed the performance of a custom TaqMan SARS-CoV-2 mutation panel consisting of 10 selected real-time PCR (RT-PCR) genotyping assays compared to whole-genome sequencing (WGS) for identification of 5 VOC circulating...

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Identifiers

PMID: 37154727
DOI: 10.1128/spectrum.03450-22
PMCID: PMC10269661

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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