Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A bidirectional 2-sample Mendelian randomization study of depressed mood and premature ovarian insufficiency.

Medicine - 13 Mar 2026

Chen Kan, Wan Li, Wang Xinmei, Ma Xiaorong, Chen Yanru, Han Lu

Abstract excerpt

This study aimed to investigate the bidirectional causal relationship between depressed mood and premature ovarian insufficiency (POI) using a Mendelian randomization (MR) method. Genome wide association study data on depressed mood and POI were obtained using the IEU Open genome wide association study website. Closely related and independent single nucleotide polymorphisms (SNPs) were screened as instrumental...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Depression
Share to Genetic Predisposition to Disease
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Share to Primary Ovarian Insufficiency

Source

Open in PubMed Open full text

Identifiers

PMID: 41824824
DOI: 10.1097/MD.0000000000048039
PMCID: PMC12991491

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A bidirectional 2-sample Mendelian randomization study of depressed mood and premature ovarian insufficiency.PMID 41824824Read ↗

Epidemiologic and genetic associations of female reproductive disorders with depression or dysthymia: a Mendelian randomization studySemantic proximity Read ↗

Causal relationship between mood swing and gynecological disorders: a Mendelian randomization studySemantic proximity Read ↗

The causal relationship of female infertility and psychiatric disorders in the European population: a bidirectional two-sample Mendelian randomization study.Semantic proximity Read ↗

Genetic Causal Association Between Vitamin E and Depression: A Two-Sample Mendelian Randomization Study.Semantic proximity Read ↗

Mendelian randomization study on the causal link between reproductive behavior and postpartum depression.Semantic proximity Read ↗

Depression, ovarian cysts and infertility in women: A mediated Mendelian randomization analysis.Semantic proximity Read ↗

Psychological distress and uterine fibroids: a bidirectional two-sample mendelian randomization study.Semantic proximity Read ↗

Genetic Liability to Antidepressant Treatment and Risk of Female Infertility: A Two-Sample Bidirectional Mendelian Randomization StudySemantic proximity Read ↗

The causal relationship of depression, anxiety, and neuroticism with endometriosis: A bidirectional 2-sample Mendelian randomization study.Semantic proximity Read ↗

Common mental disorders and risk of female infertility: a two-sample Mendelian randomization study.Semantic proximity Read ↗

Causal relationship between Women's reproductive traits and postpartum depression: a multivariate Mendelian randomization analysisSemantic proximity Read ↗

The correlation between primary ovarian insufficiency, sex hormones and immune cells: a two-step Mendelian randomization studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.