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Deep spatial proteomics reveals region-specific features of severe COVID-19-related pulmonary injury

21 Jan 2024

Abstract excerpt

As a primary target of severe acute respiratory syndrome coronavirus 2, lung exhibits heterogeneous histopathological changes following infection. However, comprehensive insight into their protein basis with spatial resolution remains deficient, which hinders further understanding of coronavirus disease 2019 (COVID-19)-related pulmonary injury. Here, we generate a region-resolved proteomic atlas of hallmark...

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PMID: 38241149
DOI: 10.1016/j.celrep.2024.113689

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