Article

Quantitative multi-organ proteomics of fatal COVID-19 uncovers tissue-specific effects beyond inflammation

2022-12-22

Abstract excerpt

SARS-CoV-2 directly damages lung tissue via its infection and replication process and indirectly due to systemic effects of the host immune system. There are few systems-wide, untargeted studies of these effects on the different tissues of the human body and nearly all of them base their conclusions on the transcriptome. Here we developed a parallelized mass spectrometry (MS)-based proteomics workflow allowing the...

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Literature Corpus work: 31f5d15a-9247-5fd3-be6f-1952af213538
DOI: 10.1101/2022.12.21.22283785

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