Article
TERT single nucleotide polymorphism rs2736098 but not rs2736100 is associated with telomere length in HIV-infected patients on cART.
Molecular biology reports - 18 Jan 2024
Bukic Ena, Dragovic Gordana, Toljic Bosko, Obradovic Bozana, Jadzic Jelena, Jevtovic Djordje, Milasin Jelena M
Abstract excerpt
BACKGROUND: Continuous application of "combination antiretroviral therapy" (cART) has transformed Human immunodeficiency virus (HIV) infection into a manageable chronic disease; however, due to lasting inflammation and cumulative toxicity, progressive pathophysiological changes do occur and potentially lead to accelerated aging, among others, contributing to telomere shortening. The single nucleotide...
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