Article
TERT rs2736100 and TERC rs16847897 genotypes moderate the association between internalizing mental disorders and accelerated telomere length attrition among HIV+ children and adolescents in Uganda.
BMC medical genomics - 6 Jan 2021
Kalungi Allan, Kinyanda Eugene, Womersley Jacqueline S, Joloba Moses L, Ssembajjwe Wilber, Nsubuga Rebecca N, Kaleebu Pontiano, Levin Jonathan, Kidd Martin, Seedat Soraya, Hemmings Sian M J
Abstract excerpt
BACKGROUND: Internalizing mental disorders (IMDs) (depression, anxiety and post-traumatic stress disorder) have been associated with accelerated telomere length (TL) attrition; however, this association has not been investigated in the context of genetic variation that has been found to influence TL. We have previously reported an association between IMDs and accelerated TL attrition among Ugandan HIV+ children...
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