Article
Prevalence and Determinants of Liver Disease in Relatives of Italian Patients With Advanced MASLD.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Nov 2024
Pelusi Serena, Ronzoni Luisa, Rondena Jessica, Rosso Chiara, Pennisi Grazia, Dongiovanni Paola, Margarita Sara, Carpani Rossana, Soardo Giorgio, Prati Daniele, Cespiati Annalisa, Petta Salvatore, Bugianesi Elisabetta, Valenti Luca
Abstract excerpt
BACKGROUND & AIMS: Metabolic dysfunction associated steatotic liver disease (MASLD) has a strong genetic component. The aim of this study was to examine noninvasively the prevalence of MASLD and of advanced fibrosis in relatives of patients with advanced MASLD and the risk factors for liver involvement, with a focus on the contribution of common genetic risk variants. METHODS: We prospectively enrolled 98...
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