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Article

Monogenic and Polygenic Risk in Common Liver Diseases: Implications for Clinical Care.

Gastroenterology - 1 Aug 2026

Ajmera Veeral, Huang Daniel Q, Chen Vincent L, Reddy K Rajender

Abstract excerpt

The burden of chronic liver disease is rapidly increasing worldwide, driven primarily by metabolic dysfunction-associated steatotic liver disease, metabolic and alcohol-associated liver disease (MetALD), and alcohol-associated liver disease (ALD). Genetic predisposition contributes substantially to variability in disease onset, progression, and outcomes, and recent advances in genomic discovery have brought...

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Source

Identifiers

PMID: 41932449
DOI: 10.1053/j.gastro.2026.03.020

Genes

HSD17B13
PNPLA3
TM6SF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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