Article
Radiation-Induced Lymphopoenia and Treatment Outcome in Hereditary Breast Cancer Patients.
Folia biologica - 1 Jan 2023
Argalácsová Soňa, Křížová Ľudmila, Matějů Martin, Svobodová Dominika, Vočka Michal
Abstract excerpt
Many breast cancer (BC) predisposition genes encode proteins involved in DNA damage repair (DDR). Identification of germline pathogenic va-riants (PV) in DDR genes raises the question whether their presence can influence the treatment outcomes and potential radiation-induced toxicity in their carriers treated by adjuvant radiotherapy, which has not yet been answered conclusively. We retrospectively examined...
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