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Vitamin D and the epigenome

29 Apr 2014

Abstract excerpt

Epigenetic mechanisms play a crucial role in regulating gene expression. The main mechanisms involve methylation of DNA and covalent modifications of histones by methylation, acetylation, phosphorylation, or ubiquitination. The complex interplay of different epigenetic mechanisms is mediated by enzymes acting in the nucleus. Modifications in DNA methylation are performed mainly by DNA methyltransferases (DNMTs)...

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PMID: 24808866
DOI: 10.3389/fphys.2014.00164

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