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Glucose dysregulation in antipsychotic-naive first-episode psychosis: in silico exploration of gene expression signatures

10 Jan 2024

Abstract excerpt

Antipsychotic (AP)-naive first-episode psychosis (FEP) patients display early dysglycemia, including insulin resistance and prediabetes. Metabolic dysregulation may therefore be intrinsic to psychosis spectrum disorders (PSDs), independent of the metabolic effects of APs. However, the potential biological pathways that overlap between PSDs and dysglycemic states remain to be identified. Using meta-analytic...

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PMID: 38199991
DOI: 10.1038/s41398-023-02716-8

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