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Article

Plasma cell-free DNA as a sensitive biomarker for multi-cancer detection and immunotherapy outcomes prediction

1 Jan 2024

Abstract excerpt

BACKGROUND: Cell-free DNA (cfDNA) has shown promise in detecting various cancers, but the diagnostic performance of cfDNA end motifs for multiple cancer types requires verification. This study aimed to assess the utility of cfDNA end motifs for multi-cancer detection. METHODS: This study included 206 participants: 106 individuals with cancer, representing 20 cancer types, and 100 healthy individuals. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38196018
DOI: 10.1007/s00432-023-05521-4

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