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FOXL2 and NR5A1 induce human fibroblasts into steroidogenic ovarian granulosa‐like cells

8 Jan 2024

Abstract excerpt

Abstract Human granulosa cells in different stages are essential for maintaining normal ovarian function, and granulosa cell defect is the main cause of ovarian dysfunction. To address this problem, it is necessary to induce functional granulosa cells at different stages in vitro. In this study, we established a reprogramming method to induce early‐ and late‐stage granulosa cells with different steroidogenic...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 38192172
DOI: 10.1111/cpr.13589

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