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Article

Differentiation of rat iPS cells and ES cells into granulosa cell-like cells in vitro.

Acta biochimica et biophysica Sinica - 1 Apr 2013

Zhang Juan, Li Hui, Wu Zhao, Tan Xiaojun, Liu Fengying, Huang Xianghong, Fang Xiaoling

Abstract excerpt

Premature ovarian failure (POF) is an ovarian defect characterized by the premature depletion of ovarian follicles before 40 years of age, representing one major cause of female infertility. Stem cells provide the possibility of a potential treatment for POF. In this study, rat embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) were co-cultured with granulosa cells (GCs) to differentiate to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23403512
DOI: 10.1093/abbs/gmt008

Genes

FSHR
AMH
BMP15
GDF9
INHA
NOBOX
FIGLA
FMR1
FOXO3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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