Article
Gene drive and genetic sex conversion in the global agricultural pest Ceratitis capitata.
Nature communications - 8 Jan 2024
Meccariello Angela, Hou Shibo, Davydova Serafima, Fawcett James Daniel, Siddall Alexandra, Leftwich Philip T, Krsticevic Flavia, Papathanos Philippos Aris, Windbichler Nikolai
Abstract excerpt
Homing-based gene drives are recently proposed interventions promising the area-wide, species-specific genetic control of harmful insect populations. Here we characterise a first set of gene drives in a tephritid agricultural pest species, the Mediterranean fruit fly Ceratitis capitata (medfly). Our results show that the medfly is highly amenable to homing-based gene drive strategies. By targeting the medfly...
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