Article

Highly efficient DNA-free gene disruption in the agricultural pest <i>Ceratitis capitata</i> by CRISPR-Cas9 RNPs

2017-04-18

Abstract excerpt

<h4>ABSTRACT</h4> The Mediterranean fruitfly Ceratitis capitata (medfly) is an invasive agricultural pest of high economical impact and has become an emerging model for developing new genetic control strategies as alternative to insecticides. Here, we report the successful adaptation of CRISPR-Cas9-based gene disruption in the medfly by injecting in vitro pre-assembled, solubilized Cas9 ribonucleoprotein comple...

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Literature Corpus work: b3632804-650c-5736-9108-d43b25995177
DOI: 10.1101/127506

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