Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multiplex Detection of Single Nucleotide Polymorphisms by Liquid Chromatography for Nonsmall Cell Lung Cancer Staging.

Analytical chemistry - 23 Jan 2024

Song Chang, Ma Ziyu, Zhang Mengyu, Liu Chang, Tang Sheng, Zhang Jinghui, Song Juan, Yu Hui, Lee Hian Kee, Shen Wei

Abstract excerpt

In this work, an integrated strategy with excellent accuracy and high throughput is proposed for the precise indication of single nucleotide polymorphism (SNP) in nonsmall cell lung cancer diseases. Two types of point mutations (L858R and T790M) and the corresponding wild types could be identified together in a single high-performance liquid chromatographic run. Signal amplification was achieved through a series...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Non-Small-Cell Lung
Share to Chromatography, Liquid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Probes

Share to ErbB Receptors

Share to Lung Neoplasms

Share to Mutation

Share to Polymorphism, Single Nucleotide

Share to Protein Kinase Inhibitors

Source

Identifiers

PMID: 38190445
DOI: 10.1021/acs.analchem.3c03659

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiplex Detection of Single Nucleotide Polymorphisms by Liquid Chromatography for Nonsmall Cell Lung Cancer Staging.PMID 38190445Read ↗

A universal approach for mutation identification with a DNA probe-enzyme combination platform.Semantic proximity Read ↗

Capillary electrophoretic genotyping of epidermal growth factor receptor for pharmacogenomic assay of lung cancer therapy.Semantic proximity Read ↗

Improvement of limit of detection in primer extension-based multiplexed mutation assay using capillary electrophoresis.Semantic proximity Read ↗

Detection of Single Nucleotide Polymorphisms of Circulating Tumor DNA by Strand Displacement Amplification Coupled with Liquid Chromatography.Semantic proximity Read ↗

Ultrasensitive Multiplex Detection of Single Nucleotide Polymorphisms Based on Short-Chain Hybridization Combined with Online Preconcentration of Capillary Electrophoresis.Semantic proximity Read ↗

Ultraspecific Multiplexed Detection of Low-Abundance Single-Nucleotide Variants by Combining a Masking Tactic with Fluorescent Nanoparticle Counting.Semantic proximity Read ↗

Inverted Sandwich-Type e-LCR Aided by Lambda Exonuclease-RecJf Combination Enables Ultrasensitive Detection of Low-Frequency EGFR-L858R Mutation in NSCLC.Semantic proximity Read ↗

A protein enzyme-free strategy for fluorescence detection of single nucleotide polymorphisms using asymmetric MNAzymes.Semantic proximity Read ↗

Single nucleotide variation detection on 3D DNA microarray by ligation of two-terminal-modified universal probes.Semantic proximity Read ↗

Enrichment of low-abundance gene mutation by a combined polymerase and ligase chain reaction.Semantic proximity Read ↗

Early Monitoring Drug Resistant Mutation T790M with a Two-Dimensional Simultaneous Discrimination Nanopore Strategy.Semantic proximity Read ↗

Genotyping of common EGFR mutations in lung cancer patients by electrochemical biosensor.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.