Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Persistent Low-Level Variants in a Subset of Viral Genes Are Highly Predictive of Poor Outcome in Immunocompromised Patients With Cytomegalovirus Infection.

The Journal of infectious diseases - 16 Aug 2024

Venturini Cristina, Colston Julia M, Charles Oscar, Lankina Anastasia, Best Timothy, Atkinson Claire, Forrest Calum, Williams Charlotte A, Rao Kanchan, Worth Austen, Thorburn Doug, Harber Mark, Griffiths Paul, Breuer Judith

Abstract excerpt

BACKGROUND: Human cytomegalovirus (HCMV) is the most common and serious opportunistic infection after solid organ and hematopoietic stem cell transplantation. In this study, we used whole-genome HCMV data to investigate viral factors associated with the clinical outcome. METHODS: We sequenced HCMV samples from 16 immunocompromised pediatric patients with persistent viremia. Eight of the 16 patients died of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus
Share to Cytomegalovirus Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Viral

Share to Genes, Viral

Share to Hematopoietic Stem Cell Transplantation

Share to Immunocompromised Host

Share to Organ Transplantation

Share to Viremia

Source

Open in PubMed Open full text

Identifiers

PMID: 38181168
DOI: 10.1093/infdis/jiae001
PMCID: PMC11326829

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Persistent Low-Level Variants in a Subset of Viral Genes Are Highly Predictive of Poor Outcome in Immunocompromised Patients With Cytomegalovirus Infection.PMID 38181168Read ↗

Persistent low-level variants in a subset of HCMV genes are highly predictive of poor outcome in immunocompromised patients with cytomegalovirus infectionSemantic proximity Read ↗

Transcriptome-wide characterization of human cytomegalovirus in natural infection and experimental latencySemantic proximity Read ↗

Characterization of Human Cytomegalovirus Genome Diversity in Immunocompromised Hosts by Whole-Genome Sequencing Directly From Clinical Specimens.Semantic proximity Read ↗

Whole-Genome Approach to Assessing Human Cytomegalovirus Dynamics in Transplant Patients Undergoing Antiviral TherapySemantic proximity Read ↗

Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA SequencingSemantic proximity Read ↗

Human Cytomegalovirus Genomes Sequenced Directly From Clinical Material: Variation, Multiple-Strain Infection, Recombination, and Gene LossSemantic proximity Read ↗

Improved detection of emerging drug-resistant mutant cytomegalovirus subpopulations by deep sequencing.Semantic proximity Read ↗

"Unusual" viral diseases after allogeneic hematopoietic stem cell transplantation: a multicenter, retrospective studySemantic proximity Read ↗

Genomic and Functional Characteristics of Human Cytomegalovirus Revealed by Next-Generation SequencingSemantic proximity Read ↗

Detection of Low Frequency Multi-Drug Resistance and Novel Putative Maribavir Resistance in Immunocompromised Pediatric Patients with CytomegalovirusSemantic proximity Read ↗

Identifying human cytomegalovirus genotypes & defining their clinical significance.Semantic proximity Read ↗

Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA SequencingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.