Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection of Low Frequency Multi-Drug Resistance and Novel Putative Maribavir Resistance in Immunocompromised Pediatric Patients with Cytomegalovirus

8 Sept 2016

Abstract excerpt

Human cytomegalovirus (HCMV) is a significant pathogen in immunocompromised individuals, with the potential to cause fatal pneumonitis and colitis, as well as increasing the risk of organ rejection in transplant patients. With the advent of new anti-HCMV drugs there is therefore considerable interest in using virus sequence data to monitor emerging resistance to antiviral drugs in HCMV viraemia and disease,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Neonatal Health and Biochemistry
Share to Pneumocystis jirovecii pneumonia detection and treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27667983
DOI: 10.3389/fmicb.2016.01317

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detection of Low Frequency Multi-Drug Resistance and Novel Putative Maribavir Resistance in Immunocompromised Pediatric Patients with CytomegalovirusPMID 27667983Read ↗

Rapid emergence of HCMV drug resistance in immunocompromised paediatric patients detected using target enrichment and deep sequencingSemantic proximity Read ↗

Human Cytomegalovirus (HCMV) Genetic Diversity, Drug Resistance Testing and Prevalence of the Resistance Mutations: A Literature ReviewSemantic proximity Read ↗

Persistent low-level variants in a subset of HCMV genes are highly predictive of poor outcome in immunocompromised patients with cytomegalovirus infectionSemantic proximity Read ↗

Improved detection of emerging drug-resistant mutant cytomegalovirus subpopulations by deep sequencing.Semantic proximity Read ↗

Detection of antiviral drug resistance in patients with congenital cytomegalovirus infection using long-read sequencing: a retrospective observational study.Semantic proximity Read ↗

Drug Resistance Mutations and Associated Phenotypes Detected in Clinical Trials of Maribavir for Treatment of Cytomegalovirus Infection.Semantic proximity Read ↗

Whole-Genome Approach to Assessing Human Cytomegalovirus Dynamics in Transplant Patients Undergoing Antiviral TherapySemantic proximity Read ↗

Novel UL97 drug resistance mutations identified at baseline in a clinical trial of maribavir for resistant or refractory cytomegalovirus infectionSemantic proximity Read ↗

The emergence of letermovir and maribavir drug-resistant mutations: from clinical trials to real-world studies.Semantic proximity Read ↗

Advances in the genotypic diagnosis of cytomegalovirus antiviral drug resistance.Semantic proximity Read ↗

Drug Resistance Assessed in a Phase 3 Clinical Trial of Maribavir Therapy for Refractory or Resistant Cytomegalovirus Infection in Transplant Recipients.Semantic proximity Read ↗

Characterization of the dynamics of human cytomegalovirus resistance to antiviral drugs by ultra-deep sequencing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.