Article
How local reference panels improve imputation in French populations.
Scientific reports - 3 Jan 2024
Herzig Anthony F, Velo-Suárez Lourdes, Dina Christian, Redon Richard, Deleuze Jean-François, Génin Emmanuelle
Abstract excerpt
Imputation servers offer the exclusive possibility to harness the largest public reference panels which have been shown to deliver very high precision in the imputation of European genomes. Many studies have nonetheless stressed the importance of 'study specific panels' (SSPs) as an alternative and have shown the benefits of combining public reference panels with SSPs. But such combined approaches are not...
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