Article

Imputation Accuracy Across Global Human Populations

2023-05-24

Abstract excerpt

Genotype imputation is now fundamental for genome-wide association studies but lacks fairness due to the underrepresentation of populations with non-European ancestries. The state-of-the-art imputation reference panel released by the Trans-Omics for Precision Medicine (TOPMed) initiative contains a substantial number of admixed African-ancestry and Hispanic/Latino samples to impute these populations with nearly th...

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Literature Corpus work: c0d92e15-54b9-5484-95a0-0fa893eda28a
DOI: 10.1101/2023.05.22.541241

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