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Direct Reprogramming of Fibroblasts to Osteoblasts: Techniques and Methodologies

30 Dec 2023

Abstract excerpt

Direct reprogramming (DR) is an emerging technique that can be applied to convert fibroblasts into osteoblast-like cells, promoting bone formation and regeneration. We review the current methodology of DR in relation to the creation of induced osteoblasts, including a comparison of transcription factor-mediated reprogramming and nontranscription factor-mediated reprogramming. We review the selection of...

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PMID: 38159082
DOI: 10.1093/stcltm/szad093

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