Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Direct conversion of fibroblasts to osteoblasts as a novel strategy for bone regeneration in elderly individuals

1 May 2019

Abstract excerpt

Mortality caused by age-related bone fractures or osteoporosis is steadily increasing worldwide as the population ages. The pace of the development of bone regeneration engineering to treat bone fractures has consequently increased in recent years. A range of techniques for bone regeneration, such as immunotherapy, allografts, and hydrogel therapy, have been devised. Cell-based therapies using bone marrow-derived...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mesenchymal stem cell research
Share to Pluripotent Stem Cells Research
Share to Tissue Engineering and Regenerative Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31073120
DOI: 10.1038/s12276-019-0251-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Direct conversion of fibroblasts to osteoblasts as a novel strategy for bone regeneration in elderly individualsPMID 31073120Read ↗

Direct Reprogramming of Fibroblasts to Osteoblasts: Techniques and MethodologiesSemantic proximity Read ↗

Direct conversion of human fibroblasts into osteoblasts and osteocytes with small molecules and a single factor, Runx2Semantic proximity Read ↗

Direct phenotypic conversion of human fibroblasts into functional osteoblasts triggered by a blockade of the transforming growth factor-β signal.Semantic proximity Read ↗

Molecular mechanisms of mesenchymal stem cell differentiation towards osteoblastsSemantic proximity Read ↗

Mesenchymal Stem Cells for Bone Gene Therapy and Tissue EngineeringSemantic proximity Read ↗

Human Fibroblasts as a Model for the Study of Bone DisordersSemantic proximity Read ↗

Generation of Directly Converted Human Osteoblasts That Are Free of Exogenous Gene and Xenogenic Protein.Semantic proximity Read ↗

Concise Review: Induced Pluripotent Stem Cells and Lineage Reprogramming: Prospects for Bone RegenerationSemantic proximity Read ↗

Review: Gene- and Stem Cell–Based Therapeutics for Bone Regeneration and RepairSemantic proximity Read ↗

Osteogenic Differentiation of Human Marrow-Derived Mesenchymal Stem CellsSemantic proximity Read ↗

From Stem Cells to Bone-Forming CellsSemantic proximity Read ↗

Mesenchymal Stem Cells: Molecular Targets for Tissue EngineeringSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.