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Article

Clinical phenogroup diversity and multiplicity: Impact on mechanisms of exercise intolerance in heart failure with preserved ejection fraction.

European journal of heart failure - 1 Mar 2024

Larson Kathryn, Omar Massar, Sorimachi Hidemi, Omote Kazunori, Alogna Alessio, Popovic Dejana, Tada Atsushi, Doi Shunichi, Naser Jwan, Reddy Yogesh N V, Redfield Margaret M, Borlaug Barry A

Abstract excerpt

AIMS: We aimed to clarify the extent to which cardiac and peripheral impairments to oxygen delivery and utilization contribute to exercise intolerance and risk for adverse events, and how this relates to diversity and multiplicity in pathophysiologic traits. METHODS AND RESULTS: Individuals with heart failure with preserved ejection fraction (HFpEF) and non-cardiac dyspnoea (controls) underwent invasive...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 38156712
DOI: 10.1002/ejhf.3105
PMCID: PMC11096073

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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