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Article

Physiologic Phenotyping of Responses to Exercise and Activity in Heart Failure.

Circulation research - 7 Jul 2025

Lewis Gregory D, Tada Atsushi, Landsteiner Isabela, Borlaug Barry A

Abstract excerpt

Subjective and objective limitations to exercise and activity are hallmarks of heart failure (HF), regardless of underlying ejection fraction (EF). These limitations relate to cardiovascular abnormalities involving the systolic and diastolic properties of the heart, venous, and arterial vasculature, as well as noncardiovascular abnormalities, including impairments in pulmonary function, autonomic regulation,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40608855
DOI: 10.1161/CIRCRESAHA.125.325534
PMCID: PMC12233139

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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