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Article

A novel ferroptosis phenotype-related clinical-molecular prognostic signature for hepatocellular carcinoma.

Journal of cellular and molecular medicine - 1 Jul 2021

Deng Tuo, Hu Bingren, Jin Chen, Tong Yifan, Zhao Jungang, Shi Zhehao, Zhang Tan, Deng Liming, Sun Zhifu, Chen Gang, Wang Yi

Abstract excerpt

Ferroptosis is a newly identified cell death mechanism and potential biomarker for hepatocellular carcinoma (HCC) therapy; however, its clinical relevance and underlying mechanism remain unclear. In this study, transcriptome and methylome data from 374 HCC cases were investigated for 41 ferroptosis-related genes to identify ferroptosis activity-associated subtypes. These subtypes were further investigated for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34085405
DOI: 10.1111/jcmm.16666
PMCID: PMC8278110

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