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A Ferroptosis–Heat Shock Response Prognostic Signature in Hepatocellular Carcinoma: Cross-Platform Validation and Independence from HSPB1–GPX4 Axis Activity

2026-06-15

Abstract excerpt

<title>Abstract</title> <p>Background Hepatocellular carcinoma (HCC) remains a leading cause of cancer mortality, and molecular biomarkers are urgently needed to refine risk stratification beyond conventional staging. Although ferroptosis and the heat shock response have each been proposed as therapeutic vulnerabilities in HCC, their prognostic interplay has not been systematically evaluated. Specifically, it is...

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Literature Corpus work
69b28b33-a87a-59f1-9ba8-64071b552057
DOI
10.21203/rs.3.rs-9719095/v1
Open publication

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A Ferroptosis–Heat Shock Response Prognostic Signature in Hepatocellular Carcinoma: Cross-Platform Validation and Independence from HSPB1–GPX4 Axis ActivityDOI 10.21203/rs.3.rs-9719095/v1
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